Damage that would be dealt by Excruciator can't be prevented.
"Though used as a piercing weapon, the tusk is more akin to a stinger, spreading pain instantly throughout the body of its victim. This specimen deserves further study." —Simic research notes
Whenever a creature is dealt damage, its controller may exile that many cards from the top of their library. They may play those cards until the end of their next turn.
You may look at the top card of your library any time. You may play lands and cast spells from the top of your library. You can't play lands or cast spells from your hand. {3}{R}: Destroy Experimental Frenzy.
When Experimental Synthesizer enters or leaves the battlefield, exile the top card of your library. Until end of turn, you may play that card. {2}{R}, Sacrifice Experimental Synthesizer: Create a 2/2 white Samurai creature token with vigilance. Activate only as a sorcery.
Draw a card, then each other player may draw a card. Whenever a card is drawn this way, Explosion of Riches deals 5 damage to target opponent chosen at random from among your opponents.
Choose any target. Reveal cards from the top of your library until you reveal a nonland card. Explosive Revelation deals damage equal to that card's mana value to that permanent or player. Put the nonland card into your hand and the rest on the bottom of your library in any order.
As an additional cost to cast this spell, you may tap any number of untapped creatures you control. This spell costs {1} less to cast for each creature tapped this way. Explosive Singularity deals 10 damage to any target.
Choose one or both — • Turn target face-down creature face up. • Exile any number of face-up creatures you control with disguise in a face-down pile, shuffle that pile, then cloak them.
Exquisite Firecraft deals 4 damage to any target. Spell mastery — If there are two or more instant and/or sorcery cards in your graveyard, this spell can't be countered.
At the beginning of your end step, if you control a creature with power 5 or greater, you may have Exuberant Firestoker deal 2 damage to target player or planeswalker. {T}: Add {C}.
The artistry of Etlan's firedancers is more spectacular when behemoths join in.
Trample Exuberant Fuseling gets +1/+0 for each oil counter on it. When Exuberant Fuseling enters the battlefield and whenever another creature or artifact you control is put into a graveyard from the battlefield, put an oil counter on Exuberant Fuseling.
I — Create a 2/2 red Goblin Shaman creature token with "Whenever this creature attacks, create a Treasure token." II — You may discard up to two cards. If you do, draw that many cards. III — Exile this Saga, then return it to the battlefield transformed under your control.